Chemistry
Our accomplished faculty serves in editorial positions with the Journal of Coordination Chemistry, Journal of Medicinal Chemistry and Drug Design, and European Chemical Bulletin, among others.
Several hold patents developed through their research, and are members and fellows of the American Chemical Society. Their impactful research on health- and materials-related chemistry contributes to answering some of society’s most pressing scientific questions.
Recent Grants include:
- Sergio Granados-Focil and Luis Smith, National Science Foundation: “An integrated study of ion dynamics and population distributions to understand the molecular underpinnings of charge transport through self-assembled solid polymer electrolytes”
- Noel Lazo, National Institutes of Health (National Institute on Aging): “Determinants of the Proteolytic Degradation of Soluble Amyloid-beta”
- Sergio Granados-Focil, in collaboration with Steven Van Dessel of WPI’s Civil Engineering Department, National Science Foundation: “Collaborative Research: Adaptive Building Enclosure Systems Using Cellular Solid-Solid Phase Change Materials With Variable Transparency”
- Donald Spratt, National Institutes of Health (National Institute of General Medical Sciences): “Structure and Mechanism of HECT E3 Ubiquitin Ligases”
Submissions from 2024
Dichloridotetrakis(3-methoxyaniline)nickel(II), Benjamin A. Mukda and Mark M. Turnbull
A Copper-Selective Sensor and Its Inhibition of Copper-Amyloid Beta Aggregation, Ngoc Kim Nguyen, Bella Poduska, Mia Franks, Manoranjan Bera, Ian MacCormack, Guoxing Lin, Alexander P. Petroff, Samir Das, and Arundhati Nag
A perspective on the stimuli-responsive photoactivities of coumarin with a focus on redox-responsive photodynamic therapy (PDT), Vineeth M. Pillai, M.M. Sreejaya, Ajula C P, Haridev M., Anju Murali, Harikrishnan K K, Manoranjan Bera, and Moumita Gangopadhyay
Mechanistic analysis of viscosity-sensitive fluorescent probes for applications in diabetes detection, M.M Sreejaya, Vineeth Pillai, A. Ayesha, Maanas Baby, Manoranjan Bera, and Moumita Gangopadhyay
The synthesis and structures of four new copper(II) adamantoid clusters, Mark M. Turnbull, Benjamin Mukda, Diane Dickie, and Jan L. Wikaira
Hydrothermal synthesis of (C5H14N2)[CoCl4]⸳0.5H2O: Crystal structure, spectroscopic characterization, thermal behavior, magnetic properties and biological evaluation, Sandra Walha, Noureddine Mhadhbi, Basem F. Ali, Abdellah Kaiba, Ahlem Guesmi, Wesam Abd El-Fattah, Naoufel Ben Hamadi, Mark M. Turnbull, Ferdinando Costantino, and Houcine Naïli
The disordered negatively charged C-terminus of the large HECT E3 ubiquitin ligase HERC2 provides structural and thermal stability to the HECT C-lobe, Kelly L. Waters, Kayla J. Rich, Noah D. Schwaegerle, Tianyi Yang, Shuanghong Huo, and Donald E. Spratt
New Discoveries on Protein Recruitment and Regulation during the Early Stages of the DNA Damage Response Pathways, Kelly Waters and Donald E. Spratt
Submissions from 2023
A copper(II) coordination polymer of formate-bridged dimers: an alternating S = ½ antiferromagnetic chain, Anthony W. Addison, Raymond Butcher, and Mark Turnbull
Pyridyl-imidazole copper compounds, Alma Araujo Martinez, Christopher L. Landee, Diane Dickie, Jan L. Wikaira, Fan Xiao, and Mark M. Turnbull
A family of methoxide-bridged Cu(II) compounds with N-heterocyclic ligands: dimers and chains, Alma P. Araujo-Martinez, Kesli Faber, Diane A. Dickie, Christopher P. Landee, Mark M. Turnbull, Brendan Twamley, and Nathan Huynh
Halogen bond and polymorphism in trans-bis(2-iodo-5-halopyridine)dihalocopper(ii) complexes: crystallographic, theoretical and magnetic studies, Firas F. Awwadi, Manal I. Alwahsh, Mark M. Turnbull, and Christopher Landee
Copper(II) halide salts of 5-bromo-2-aminopyridine and 3,5-dibromo-2-aminopyridine: syntheses, structures and magnetic behavior, Charlotte P. Bedford, Christopher Landee, Mark M. Turnbull, and Jan L. Wikaira
Facile de Novo Sequencing of Tetrazine-Cyclized Peptides through UV-Induced Ring-Opening and Cleavage from the Solid Phase, Ariane Borges, Chi Nguyen, Madison Letendre, Iryna Onasenko, Rene Kandler, Ngoc K. Nguyen, Jue Chen, Tamara Allakhverdova, Emily Atkinson, Bella DiChiara, Caroline Wang, Noa Petler, Henna Patel, Dhaval Nanavati, Samir Das, and Arundhati Nag
The odd-even effect in n-carboxyalkylammonium-containing organic-inorganic hybrids of Mn(ii) halides: structural and magnetic characterisation, Shalene N. Bothma, Charles J. Sheppard, Mark M. Turnbull, Christopher P. Landee, and Melanie Rademeyer
Crystal Chemistry, Optic and Magnetic Characterizations of a New Copper Based Material Templated by Hexahydrodiazepine, Mansoura Bourwina, Rawia Msalmi, Sandra Walha, Mark M. Turnbull, Thierry Roisnel, Ahlem Guesmi, Ammar Houas, Naoufel Ben Hamadi, and Houcine Naïli
Organic–Inorganic Manganese (II) Halide Hybrid Combining the Two Isomers Cis/Trans of [MnCl4(H2O)2]: Crystal Structure, Physical Properties, Pharmacokinetics and Biological Evaluation, Mansoura Bourwina, Sandra Walha, Najeh Krayem, Riadh Badraoui, Faten Brahmi, Mark M. Turnbull, Wejdan M. Alshammari, Mejdi Snoussi, Thierry Roisnel, and Houcine Naïli
Synthesis of copper(II) halide dimers with 2-amino-5-methylpyridine and serendipitous copper catalyzed synthesis of 3-bromo-2-ethyl-5-methyl-1H-pyrrolo[2,3-b]pyridine, Carina L. Chittim, Kesli Faber, Diane A. Dickie, Christopher Landee, Shane G. Telfer, and Mark M. Turnbull
Satellite ligand effects on magnetic exchange in dimers. A structural, magnetic and theoretical investigation of Cu2L2X4 (L = methylisothiazolinone and X = Cl−, Br−), Stefan Coetzee, Mark M. Turnbull, Christopher Landee, Jeffrey C. Monroe, Mercè Deumal, Juan J. Novoa, and Melanie Rademeyer
Long-Term Stability of Ferri-/Ferrocyanide as an Electroactive Component for Redox Flow Battery Applications: On the Origin of Apparent Capacity Fade, Eric M. Fell, Diana De Porcellinis, Yan Jing, Valeria Gutierrez-Venegas, Thomas Y. George, Roy G. Gordon, Sergio Granados-focil, and Michael Aziz
Copper(II) halide complexes of aminopyridines: Synthesis, structure, and magnetic behavior of neutral compounds of 5-IAP: (5-IAP)2CuCl2·H2O, [(5-IAP)2CuBr2]2, (5-IAP)2CuBr2 and (5-IAP)3CuCl2·nH2O (5IAP = 2-amino-5-iodopyridine), Nathan V. Huynh, Lixin Li, Christopher Landee, Louise N. Dawe, Diane A. Dickie, Mark M. Turnbull, and Jan. L. Wikaira
How to Identify-with as Little as One Question-Students Who Are Likely to Struggle in Undergraduate Organic Chemistry, Charles E. Jakobsche
Incorporating an Intelligent Tutoring System into the DiscoverOChem Learning Platform, Charles E. Jakobsche, Pitipat Kongsomjit, Conor Milson, Wenxing Wang, and Chun-Kit Ngan
An Organic Chemistry Activity to Improve Student Understanding of Molecules as 3-Dimensional Objects, Charles E. Jakobsche and Anh Vy Le
Modulation of the Activity of the Insulin-Degrading Enzyme by Aβ Peptides, Merc M. Kemeh and Noel Lazo
