Chemistry

 

Chemistry and Biochemistry

Our accomplished faculty serves in editorial positions with the Journal of Coordination Chemistry, Journal of Medicinal Chemistry and Drug Design, and European Chemical Bulletin, among others.

Several hold patents developed through their research, and are members and fellows of the American Chemical Society. Their impactful research on health- and materials-related chemistry contributes to answering some of society’s most pressing scientific questions.

Recent Grants include:

  • Sergio Granados-Focil and Luis Smith, National Science Foundation: “An integrated study of ion dynamics and population distributions to understand the molecular underpinnings of charge transport through self-assembled solid polymer electrolytes”
  • Noel Lazo, National Institutes of Health (National Institute on Aging): “Determinants of the Proteolytic Degradation of Soluble Amyloid-beta”
  • Sergio Granados-Focil, in collaboration with Steven Van Dessel of WPI’s Civil Engineering Department, National Science Foundation: “Collaborative Research: Adaptive Building Enclosure Systems Using Cellular Solid-Solid Phase Change Materials With Variable Transparency”
  • Donald Spratt, National Institutes of Health (National Institute of General Medical Sciences): “Structure and Mechanism of HECT E3 Ubiquitin Ligases”

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Submissions from 2023

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How to Identify-with as Little as One Question-Students Who Are Likely to Struggle in Undergraduate Organic Chemistry, Charles E. Jakobsche

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Incorporating an Intelligent Tutoring System into the DiscoverOChem Learning Platform, Charles E. Jakobsche, Pitipat Kongsomjit, Conor Milson, Wenxing Wang, and Chun-Kit Ngan

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Modulation of the Activity of the Insulin-Degrading Enzyme by Aβ Peptides, Merc M. Kemeh and Noel Lazo

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Tetrahalidocuprate(II) complexes with substituted pyridinium ions: effects of halide substitution, Lixin Li, Alexander Shapiro, Firas F. Awwadi, Christopher P. Landee, Mark M. Turnbull, and Jan L. Wikaira

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Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions, Arundhati Nag, Amirhossein Mafi, Samir Das, Mary Beth Yu, Belen Alvarez-Villalonga, Soo-Kyung Kim, Yapeng Su, William A. Goddard, and James R. Heath

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μ-1,6-Dioxo-1,6-diphenylhexane-3,4-diolato-bis[(2,2′-bipyridine)chloridocopper(II)] dihydrate a; b; a, Luke Nye, Shane G. Tefler, and Mark M. Turnbull

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Field-Tunable Berezinskii-Kosterlitz-Thouless Correlations in a Heisenberg Magnet, D. Opherden, M.S.J. Tepaske, F. Bärtl, M. Weber, M.M Turnbull, T. Lancaster, S.J. Blundell, M. Baenitz, J. Wosnitza, C.P. Landee, R. Moessner, and D.J. Luitz

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Linear Mn(II)4Ln(III)2 (Ln = Gd, Dy, Tb) heterometallic complexes from a ditopic hydrazone ligand: Slow magnetic relaxation in Mn4Dy2 complex, Azeem Shakeel, Hamed Bakhshi, Touqeer Ahmed, Lara Watanabe, Mark Turnbull, Ahmed Al-Harrasi, and Muhammad U. Anwar

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Structural properties of optically clear bacterial cellulose produced by Komagataeibacter hansenii using arabitol, Elizabeth M. van Zyl, Mitchell A. Kennedy, Wendy Nason, Sawyer J. Fenlon, Eric M. Young, Luis J. Smith, Surita R. Bhatia, and Jeannine M. Coburn

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Crystal growth, Hirshfeld analysis, thermal behavior and magnetic properties of a new hybrid material (C5H14N2)[MnCl3(H2O)3]Cl, Sandra Walha, Basem F. Ali, Abdellah Kaiba, Mark M. Turnbull, and Thierry Roisnel

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Synthesis, Structural, Magnetic and Computational Studies of a One-Dimensional Ferromagnetic Cu(II) Chain Assembled from a New Schiff Base Ligand, Anne Worrell, Gabriele Delle Monache, Mark M. Turnbull, Jeremy M. Rawson, Theocharis C. Stamatatos, and Melanie Pilkington

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Challenges and Strategies for Synthesizing Glutamyl Hydrazide Containing Peptides, Muyum Xu, Nicholas S. MacArthur, Chau Minh Duong, Saadman Islam, Joseph P. McElwee, and Charles E. Jakobsche