Chemistry

 

Chemistry and Biochemistry

Our accomplished faculty serves in editorial positions with the Journal of Coordination Chemistry, Journal of Medicinal Chemistry and Drug Design, and European Chemical Bulletin, among others.

Several hold patents developed through their research, and are members and fellows of the American Chemical Society. Their impactful research on health- and materials-related chemistry contributes to answering some of society’s most pressing scientific questions.

Recent Grants include:

  • Sergio Granados-Focil and Luis Smith, National Science Foundation: “An integrated study of ion dynamics and population distributions to understand the molecular underpinnings of charge transport through self-assembled solid polymer electrolytes”
  • Noel Lazo, National Institutes of Health (National Institute on Aging): “Determinants of the Proteolytic Degradation of Soluble Amyloid-beta”
  • Sergio Granados-Focil, in collaboration with Steven Van Dessel of WPI’s Civil Engineering Department, National Science Foundation: “Collaborative Research: Adaptive Building Enclosure Systems Using Cellular Solid-Solid Phase Change Materials With Variable Transparency”
  • Donald Spratt, National Institutes of Health (National Institute of General Medical Sciences): “Structure and Mechanism of HECT E3 Ubiquitin Ligases”

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Submissions from 2024

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Coordination complexes of isoquinoline with cobalt and nickel halides, Michelle A. Bellerive, Michael T. Kebede, Diane A. Dickie, Christopher Landee, Melanie Rademeyer, and Mark Turnbull

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Copper(II) salts and complexes of 2-amino-5-nitropyridine*, Andrew G. Bellesis, Alexander J. Villani-Gale, Diane A. Dickie, Jerry P. Jasinki, Christopher Landee, Jan L. Wikaira, Roger D. Willett, and Mark M. Turnbull

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Tetrazine cyclized peptides for one-bead-one-compound library: Synthesis and sequencing, Samir Das and Arundhati Nag

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Synthesis, coordination modes, structures, and magnetic properties of halogen-substituted 2-hydroxypyridine, Mathew R. Graci, Firas F. Awwadi, Diane A. Dickie, Christopher Landee, and Mark M. Turnbull

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Synthesis and evaluation of 2,5-substituted pyrimidines as small-molecule gankyrin binders, Dipti Kanabar, Emma I. Kane, Tejashri Chavan, Taylor M. Laflamme, Ethan Suarez, Mimansa Goyal, Vivek Gupta, Donald E. Spratt, and Aaron Muth

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Development of Novel Immobilized Copper–Ligand Complex for Click Chemistry of Biomolecules, Rene Kandler, Yomal Benaragama, Manoranjan Bera, Caroline Wang, Rasheda Aktar Samiha, W.M.C. Sameera, Samir Das, and Arundhati Nag

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Highly toxic Aβ begets more Aβ, Merc M. Kemeh and Noel Lazo

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Copper(II) complexes of hindered diazines: methylquinoxalines, Christopher Landee, Mark M. Turnbull, Diane A. Dickens, Brendan Twambley, and Jan L. Wikaira

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Well isolated copper(II) pyrazine-bridged chains: synthesis and magneto-structural analysis of 2-halo-4-pyridone perchlorate complexes, Jeffrey C. Monroe, Christopher P. Landee, Mark M. Turnbull, and Jan L. Wikaira

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Di­chlorido­tetra­kis­(3-meth­­oxy­aniline)nickel(II), Benjamin A. Mukda and Mark M. Turnbull

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A Copper-Selective Sensor and Its Inhibition of Copper-Amyloid Beta Aggregation, Ngoc Kim Nguyen, Bella Poduska, Mia Franks, Manoranjan Bera, Ian MacCormack, Guoxing Lin, Alexander P. Petroff, Samir Das, and Arundhati Nag

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A perspective on the stimuli-responsive photoactivities of coumarin with a focus on redox-responsive photodynamic therapy (PDT), Vineeth M. Pillai, M.M. Sreejaya, Ajula C P, Haridev M., Anju Murali, Harikrishnan K K, Manoranjan Bera, and Moumita Gangopadhyay

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Mechanistic analysis of viscosity-sensitive fluorescent probes for applications in diabetes detection, M.M Sreejaya, Vineeth Pillai, A. Ayesha, Maanas Baby, Manoranjan Bera, and Moumita Gangopadhyay

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The synthesis and structures of four new copper(II) adamantoid clusters, Mark M. Turnbull, Benjamin Mukda, Diane Dickie, and Jan L. Wikaira

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Hydrothermal synthesis of (C5H14N2)[CoCl4]⸳0.5H2O: Crystal structure, spectroscopic characterization, thermal behavior, magnetic properties and biological evaluation, Sandra Walha, Noureddine Mhadhbi, Basem F. Ali, Abdellah Kaiba, Ahlem Guesmi, Wesam Abd El-Fattah, Naoufel Ben Hamadi, Mark M. Turnbull, Ferdinando Costantino, and Houcine Naïli

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New Discoveries on Protein Recruitment and Regulation during the Early Stages of the DNA Damage Response Pathways, Kelly Waters and Donald E. Spratt

Submissions from 2023

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A copper(II) coordination polymer of formate-bridged dimers: an alternating S = ½ antiferromagnetic chain, Anthony W. Addison, Raymond Butcher, and Mark Turnbull

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Pyridyl-imidazole copper compounds, Alma Araujo Martinez, Christopher L. Landee, Diane Dickie, Jan L. Wikaira, Fan Xiao, and Mark M. Turnbull

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A family of methoxide-bridged Cu(II) compounds with N-heterocyclic ligands: dimers and chains, Alma P. Araujo-Martinez, Kesli Faber, Diane A. Dickie, Christopher P. Landee, Mark M. Turnbull, Brendan Twamley, and Nathan Huynh

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Halogen bond and polymorphism in trans-bis(2-iodo-5-halopyridine)dihalocopper(ii) complexes: crystallographic, theoretical and magnetic studies, Firas F. Awwadi, Manal I. Alwahsh, Mark M. Turnbull, and Christopher Landee

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Copper(II) halide salts of 5-bromo-2-aminopyridine and 3,5-dibromo-2-aminopyridine: syntheses, structures and magnetic behavior, Charlotte P. Bedford, Christopher Landee, Mark M. Turnbull, and Jan L. Wikaira

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The odd-even effect in n-carboxyalkylammonium-containing organic-inorganic hybrids of Mn(ii) halides: structural and magnetic characterisation, Shalene N. Bothma, Charles J. Sheppard, Mark M. Turnbull, Christopher P. Landee, and Melanie Rademeyer

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Crystal Chemistry, Optic and Magnetic Characterizations of a New Copper Based Material Templated by Hexahydrodiazepine, Mansoura Bourwina, Rawia Msalmi, Sandra Walha, Mark M. Turnbull, Thierry Roisnel, Ahlem Guesmi, Ammar Houas, Naoufel Ben Hamadi, and Houcine Naïli

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Organic–Inorganic Manganese (II) Halide Hybrid Combining the Two Isomers Cis/Trans of [MnCl4(H2O)2]: Crystal Structure, Physical Properties, Pharmacokinetics and Biological Evaluation, Mansoura Bourwina, Sandra Walha, Najeh Krayem, Riadh Badraoui, Faten Brahmi, Mark M. Turnbull, Wejdan M. Alshammari, Mejdi Snoussi, Thierry Roisnel, and Houcine Naïli

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Synthesis of copper(II) halide dimers with 2-amino-5-methylpyridine and serendipitous copper catalyzed synthesis of 3-bromo-2-ethyl-5-methyl-1H-pyrrolo[2,3-b]pyridine, Carina L. Chittim, Kesli Faber, Diane A. Dickie, Christopher Landee, Shane G. Telfer, and Mark M. Turnbull