Chemistry
Our accomplished faculty serves in editorial positions with the Journal of Coordination Chemistry, Journal of Medicinal Chemistry and Drug Design, and European Chemical Bulletin, among others.
Several hold patents developed through their research, and are members and fellows of the American Chemical Society. Their impactful research on health- and materials-related chemistry contributes to answering some of society’s most pressing scientific questions.
Recent Grants include:
- Sergio Granados-Focil and Luis Smith, National Science Foundation: “An integrated study of ion dynamics and population distributions to understand the molecular underpinnings of charge transport through self-assembled solid polymer electrolytes”
- Noel Lazo, National Institutes of Health (National Institute on Aging): “Determinants of the Proteolytic Degradation of Soluble Amyloid-beta”
- Sergio Granados-Focil, in collaboration with Steven Van Dessel of WPI’s Civil Engineering Department, National Science Foundation: “Collaborative Research: Adaptive Building Enclosure Systems Using Cellular Solid-Solid Phase Change Materials With Variable Transparency”
- Donald Spratt, National Institutes of Health (National Institute of General Medical Sciences): “Structure and Mechanism of HECT E3 Ubiquitin Ligases”
Submissions from 2016
A regio- and stereo-selective annulation to form the 'inside-out' trans-bicyclo[9.2.1]tetradecane ring system, Michael B. Reardon, Brooke C. Yasgur, and Charles E. Jakobsche
Spectroscopic tracking of mechanochemical reactivity and modification of a hydrothermal char, Michael T. Timko, Alex R. Maag, Juan Mauricio Venegas, Brendan McKeogh, Zhengyang Yang, Geoffrey A. Tompsett, Simón Escapa, Joseph Toto, Erin Heckley, and Frederick T. Greenaway
Submissions from 2015
Rapid microwave-assisted grafting of layered perovskites with n-alcohols, Joshua R. Boykin and Luis J. Smith
Network representation of conformational transitions between hidden intermediates of Rd-apocytochrome b562, Mojie Duan, Hanzhong Liu, Minghai Li, and Shuanghong Huo
Stimuli-Responsive Polymers as Active Layers for Sensors, Sergio Granados-Focil
Using N-nitrosodichloroacetamides to conveniently convert linear primary amines into alcohols, Nicholas S. Macarthur, Linshu Wang, Blaine G. Mccarthy, and Charles E. Jakobsche
Robust and Ultrasensitive Polymer Membrane-Based Carbonate-Selective Electrodes, Lukasz Mendecki, Tolulope Fayose, Kelli A. Stockmal, Jia Wei, Sergio Granados-Focil, Christina M. McGraw, and Aleksandar Radu
Nanostructured ion gels from liquid crystalline block copolymers and gold nanoparticles in ionic liquids: Manifestation of mechanical and electrochemical properties, Chi Thanh Nguyen, Yumin Zhu, Xiaorui Chen, Gregory A. Sotzing, Sergio Granados-Focil, and Rajeswari M. Kasi
Role of annexin A6 in cancer (Review), Houbao Qi, Shuqing Liu, Chunmei Guo, Jiasheng Wang, Frederick T. Greenaway, and Ming Zhong Sun
K114 (trans, trans)-bromo-2,5-bis(4-hydroxystyryl)benzene is an efficient detector of cationic amyloid fibrils, Veli Selmani, Kevin J. Robbins, Valerie A. Ivancic, and Noel D. Lazo
Co(II), Cu(II), Mn(II) and Ni(II) complexes of maleic hydrazide, Khaled A. Shennara, Ray J. Butcher, and Frederick T. Greenaway
Submissions from 2014
Poly(ethylenimine)-based polymer blends as single-ion lithium conductors, Robert P. Doyle, Xiaorui Chen, Max Macrae, Abhijit Srungavarapu, Luis J. Smith, Manesh Gopinadhan, Chinedum O. Osuji, and Sergio Granados-Focil
Euclidean sections of protein conformation space and their implications in dimensionality reduction, Mojie Duan, Minghai Li, Li Han, and Shuanghong Huo
Overcoming the inherent alkylation selectivity of 2,3-trans-3,4-cis- trisubstituted cyclopentanones, Michael B. Reardon, George W. Carlson, and Charles E. Jakobsche
Mediated kinetic medium effect in the reaction of bis-3,5-di-iso- propylsalicylatozinc(II) with tert-butylperoxyl radicals, Levon A. Tavadyan, Makich Musaelyan, Seyran H. Minasyan, and Frederick T. Greenaway
Submissions from 2013
Evaluation of dimensionality-reduction methods from peptide folding-unfolding simulations, Mojie Duan, Jue Fan, Minghai Li, Li Han, and Shuanghong Huo
Potential role of annexin A7 in cancers, Chunmei Guo, Shuqing Liu, Frederick Greenaway, and Ming Zhong Sun
ACTB in cancer, Chunmei Guo, Shuqing Liu, Jiasheng Wang, Ming Zhong Sun, and Frederick T. Greenaway
Exploring binding and effector functions of natural human antibodies using synthetic immunomodulators, Charles E. Jakobsche, Christopher G. Parker, Ran N. Tao, Mariya D. Kolesnikova, Eugene F. Douglass, and David A. Spiegel
Graph representation of protein free energy landscape, Minghai Li, Mojie Duan, Jue Fan, Li Han, and Shuanghong Huo
Submissions from 2012
Conformations of Islet Amyloid Polypeptide Monomers in a Membrane Environment: Implications for Fibril Formation, Mojie Duan, Jue Fan, and Shuanghong Huo
Kinetic profile of amyloid formation in the presence of an aromatic inhibitor by nuclear magnetic resonance, Gai Liu, Jennifer C. Gaines, Kevin J. Robbins, and Noel D. Lazo
Helix-dipole effects in peptide self-assembly to amyloid, Gai Liu, Kevin J. Robbins, Samuel Sparks, Veli Selmani, Kalin M. Bilides, Erin E. Gomes, and Noel D. Lazo
Effects of two solvent conditions on the free energy landscape of the BBL peripheral subunit binding domain, Hanzhong Liu and Shuanghong Huo
Conformational analysis of thioflavin T bound to the surface of amyloid fibrils, Kevin J. Robbins, Gai Liu, Veli Selmani, and Noel D. Lazo
