Physics
Self-organized periodicity of protein clusters in growing bacteria
Document Type
Article
Abstract
Chemotaxis receptors in E. coli form clusters at the cell poles and also laterally along the cell body, and this clustering plays an important role in signal transduction. Recently, experiments using fluorescence imaging have shown that, during cell growth, lateral clusters form at positions approximately periodically spaced along the cell body. In this Letter, we demonstrate within a lattice model that such spatial organization could arise spontaneously from a stochastic nucleation mechanism. The same mechanism may explain the recent observation of periodic aggregates of misfolded proteins in E. coli. © 2008 The American Physical Society.
Publication Title
Physical Review Letters
Publication Date
11-20-2008
Volume
101
Issue
21
ISSN
0031-9007
DOI
10.1103/PhysRevLett.101.218101
Keywords
agglomeration, biochemistry, Escherichia coli, growth kinetics, signal transduction, stochastic models
Repository Citation
Wang, Hui; Wingreen, Ned S.; and Mukhopadhyay, Ranjan, "Self-organized periodicity of protein clusters in growing bacteria" (2008). Physics. 159.
https://commons.clarku.edu/faculty_physics/159
Cross Post Location
Student Publications
