Physics
Modeling the dynamics of dendritic actin waves in living cells
Document Type
Article
Abstract
The actin cytoskeleton in living cells exhibits a high degree of capacity for dynamic self-organization. Recent experiments have observed propagating actin waves in Dictyostelium cells recovering from complete depolymerization of their actin cytoskeleton. The propagation of these waves appear to be dependent on a programmed recruitment of a few proteins that control actin assembly and disassembly. Such waves also arise spontaneously along the plasma membrane of the cell, and it has been suggested that actin waves enable the cell to scan a surface for particles to engulf. Based on known molecular components involved in wave propagation, we present and study a minimal reaction-diffusion model for actin wave production observed in recovering cells.
Publication Title
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
Publication Date
11-10-2014
Volume
90
Issue
5
ISSN
1539-3755
DOI
10.1103/PhysRevE.90.052707
Keywords
cell membranes, cytology, wave propagation
Repository Citation
Wasnik, Vaibhav and Mukhopadhyay, Ranjan, "Modeling the dynamics of dendritic actin waves in living cells" (2014). Physics. 152.
https://commons.clarku.edu/faculty_physics/152
