Physics
Document Type
Article
Abstract
Chemotaxic receptors in bacteria form clusters at cell poles and also laterally, and this clustering plays an important role in signal transduction. These clusters were found to be periodically arranged on the surface of the bacterium Escherichia coli, independent of any known positioning mechanism. In this work we extend a model based on diffusion and aggregation to more realistic geometries and present a means based on 'bursty' protein production to distinguish spontaneous positioning from an independently existing positioning mechanism. We also consider the case of isotropic cellular growth and characterize the degree of order arising spontaneously. Our model could also be relevant for other examples of periodically positioned protein clusters in bacteria.
Publication Title
New Journal of Physics
Publication Date
10-11-2017
Volume
19
Issue
10
ISSN
1367-2630
DOI
10.1088/1367-2630/aa8247
Keywords
cell growth, protein cluster positioning, sub cellular protein organization
Repository Citation
Wasnik, Vaibhav; Wang, Hui; Wingreen, Ned S.; and Mukhopadhyay, Ranjan, "Physical model of protein cluster positioning in growing bacteria" (2017). Physics. 150.
https://commons.clarku.edu/faculty_physics/150
Cross Post Location
Student Publications
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright Conditions
Wasnik, V., Wang, H., Wingreen, N. S., & Mukhopadhyay, R. (2017). Physical model of protein cluster positioning in growing bacteria. New journal of physics, 19(10), 105004.
