"Characterization of fungal carbonyl sulfide hydrolase belonging to cla" by Ryuka Iizuka, Takahiro Ogawa et al.
 

Biology

Document Type

Article

Abstract

Carbonyl sulfide hydrolase (COSase) is a unique enzyme that exhibits high activity towards carbonyl sulfide (COS) but low carbonic anhydrase (CA) activity, despite belonging to the CA family. COSase was initially identified in a sulfur-oxidizing bacterium and later discovered in the ascomycete Trichoderma harzianum strain THIF08. The COSase from T. harzianum has been recognized as a key enzyme in the assimilation of gaseous COS, and homologous genes are widely present not only in Ascomycota but also in Basidiomycota. Here, we characterized the COSases from the basidiomycete Gloeophyllum trabeum NBRC 6430 and T. harzianum to obtain detailed characteristics of fungal COSase. This study contributes to a better understanding of COS metabolism in fungi.

Publication Title

FEBS Letters

Publication Date

2025

ISSN

0014-5793

DOI

10.1002/1873-3468.15098

Keywords

carbonic anhydrase, carbonyl sulfide, carbonyl sulfide hydrolase, fungi, sulfur metabolism

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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